(2S)-2-hydroxy-3-(4-phenylmethoxyphenyl)propanoic acid methyl ester - Names and Identifiers
(2S)-2-hydroxy-3-(4-phenylmethoxyphenyl)propanoic acid methyl ester - Physico-chemical Properties
Molecular Formula | C17H18O4
|
Molar Mass | 286.32 |
Density | 1.186g/cm3 |
Boling Point | 438.6°C at 760 mmHg |
Flash Point | 158.5°C |
Vapor Presure | 1.81E-08mmHg at 25°C |
Storage Condition | 2-8°C |
Refractive Index | 1.572 |
(2S)-2-hydroxy-3-(4-phenylmethoxyphenyl)propanoic acid methyl ester - Introduction
(S)-3-(4-benzyloxy-phenyl)-2-hydroxy-propionic acid methyl ester is a compound also known as (S)-3-(4-benzyloxy-phenyl)-2-hydroxy-propionic acid methyl ester. The following is a detailed description of the properties, uses, preparation methods and safety information of the compound:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C16H16O4
-Molecular weight: 272.3g/mol
-Melting point: 80-83°C
-Solubility: Soluble in organic solvents such as chloroform, methanol and dichloromethane
Use:
(S)-3-(4-benzyloxy-phenyl)-2-hydroxy-propionic acid methyl ester is often used as an important intermediate in the field of organic synthesis. It can be used to synthesize drugs, pesticides and biologically active compounds.
Preparation Method:
The preparation of (S)-3-(4-benzyloxy-phenyl)-2-hydroxy-propionic acid methyl ester can be carried out by the following steps:
1.4-benzyloxybenzyl alcohol is reacted with sodium hydroxide in methanol to generate 4-benzyloxybenzyl alcohol sodium salt.
2. To the reaction solution, (S)-2-hydroxy-propionic acid methyl ester was added to perform an esterification reaction.
3. Centrifugal filtration to obtain the product, and further crystallization purification can obtain the target product.
Safety Information:
Use and handle (S)-3-(4-benzyloxy-phenyl)-2-hydroxy-propionic acid methyl ester with caution and follow the following safety practices:
-Wear appropriate personal protective equipment such as goggles and gloves when performing laboratory operations.
-Avoid contact with skin, eyes and respiratory tract. In case of contact, rinse immediately with plenty of water and seek medical help.
-Store in a closed container, away from fire and high temperature.
-In the use of the process should follow the safety procedures of the laboratory, avoid inhalation and intake.
Last Update:2024-04-09 15:17:58